Bromperidol free base · Synonyms: R-11333

Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2.

For research use only. Not for human or veterinary use.

Target Dopamine Receptor Bacterial

Research area Infection Neurological Disease

Purity >98% Stock Inquire

Data Sheet SDS COA

Bromperidol structure

CAS No.: 10457-90-6

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 360.00	BP-02181-250mg	In stock	Get quote
500 mg	USD 570.00	BP-02181-500mg	In stock	Get quote
1 g	USD 920.00	BP-02181-1g	In stock	Get quote
2 g	USD 1,450.00	BP-02181-2g	In stock	Get quote
3 g	USD 1,750.00	BP-02181-3g	In stock	Get quote
5 g	USD 2,300.00	BP-02181-5g	In stock	Get quote
10 g	USD 4,500.00	BP-02181-10g	In stock	Get quote

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Description

Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin .

Biological activity

In Vivo Bromperidol antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats. Bromperidol antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs.

Identifiers

SMILES: O=C(C1=CC=C(F)C=C1)CCCN2CCC(O)(C3=CC=C(Br)C=C3)CC2
InChIKey: RKLNONIVDFXQRX-UHFFFAOYSA-N

Specifications

MW (average): 420.3150
Formula: C₂₁H₂₃BrFNO₂
CAS No.: 10457-90-6
Physical state: Solid
Color: White to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;

Solubility

soluble in DMSO

Documents

References

[1]. Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35(6):670-84.

[2]. Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9.

Same target

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Same research area

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