SQ109 free base · Synonyms: SQ-109 · SQ 109

SQ109 is a potent inhibitor of the trypomastigote form of the parasite.

For research use only. Not for human or veterinary use.

Target Parasite Bacterial Antibiotic

Research area Infection

Purity >98% Stock Inquire

Data Sheet SDS COA

SQ109 structure

CAS No.: 502487-67-4

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
100 mg	USD 780.00	BP-02127-100mg	In stock	Get quote
250 mg	USD 1,520.00	BP-02127-250mg	In stock	Get quote
500 mg	USD 2,400.00	BP-02127-500mg	In stock	Get quote
1 g	USD 3,800.00	BP-02127-1g	In stock	Get quote

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Description

SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent.

Identifiers

SMILES: C\C(C)=C/CC\C(C)=C\CNCCNC1C2CC3CC(C2)CC1C3
InChIKey: JFIBVDBTCDTBRH-REZTVBANSA-N

Specifications

MW (average): 330.5505
Formula: C₂₂H₃₈N₂
CAS No.: 502487-67-4
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. Veiga-Santos P, et al. SQ109, a new drug lead for Chagas disease. Antimicrob Agents Chemother. 2015 Apr;59(4):1950-61.

[2]. Jia L, et al. Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol. 2005 Jan;144(1):80-7

[3]. Jia L, et al. Interspecies pharmacokinetics and in vitro metabolism of SQ109. Br J Pharmacol. 2006 Mar;147(5):476-85.

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