BAY 2416964 free base · Synonyms: BAY-2416964 · BAY2416964
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50…
For research use only. Not for human or veterinary use.
BAY 2416964 structure
CAS No.: 2242464-44-2
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 100 mg | USD 385.00 | BP-01994-100mg | In stock | Get quote |
| 250 mg | USD 685.00 | BP-01994-250mg | In stock | Get quote |
| 500 mg | USD 1,085.00 | BP-01994-500mg | In stock | Get quote |
| 1 g | USD 1,585.00 | BP-01994-1g | In stock | Get quote |
| 5 g | Inquire | BP-01994-5g | Inquire | Inquire |
Need another size or custom synthesis? Request a quote.
Description
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment.
Biological activity
In Vitro BAY 2416964 (Example 192) induces AHR-regulated gene CYP1A1 expression in a human monocytic U937 cells with an IC50 of 4.3 nM.
Identifiers
- SMILES
-
O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CN(C)N=C3)C1=O)N[C@@H](C)CO - InChIKey
-
YAGSZKAJPHGVOV-NSHDSACASA-N
Specifications
- MW (average)
- 387.8200
- Formula
- C18H18ClN5O3
- CAS No.
- 2242464-44-2
- Physical state
- Solid
- Color
- Light yellow to green yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4℃ 2 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO