Conteltinib free base · Synonyms: CT-707
Conteltinib (CT-707) is a multi-kinase inhibitor targeting FAK, ALK, and Pyk2.
For research use only. Not for human or veterinary use.
Conteltinib structure
CAS No.: 1384860-29-0
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 50 mg | USD 880.00 | BP-02358-50mg | In stock | Get quote |
| 100 mg | USD 1,350.00 | BP-02358-100mg | In stock | Get quote |
| 500 mg | Inquire | BP-02358-500mg | In stock | Inquire |
| 1 g | Inquire | BP-02358-1g | In stock | Inquire |
Need another size or custom synthesis? Request a quote.
Description
Conteltinib (CT-707) is a multi-kinase inhibitor targeting FAK, ALK, and Pyk2. Conteltinib exerts significant inhibitory effect on FAK with an IC50 of 1.6 nM.
Biological activity
Conteltinib (CT-707) is a potent second-generation mesenchymal lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI) with antitumor activity for studies related to hepatocellular carcinoma (HCC).
Identifiers
- SMILES
-
O=S(C1=C(C=CC=C1)NC2=C(CCN3)C3=NC(NC(C=CC(N4CCC(N5CCN(C)CC5)CC4)=C6)=C6OC)=N2)(NC(C)C)=O - InChIKey
-
NPJCURIANJMFEO-UHFFFAOYSA-N
Specifications
- MW (average)
- 635.8230
- Formula
- C32H45N9O3S
- CAS No.
- 1384860-29-0
- Physical state
- Solid
- Color
- Light yellow to yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20℃ 2 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO
- In vitro
- DMSO 31.25 mg/mL