BiochemProbe — Life Science Research Reagents

BAY-5000 other · Synonyms: BAY 5000 · BAY5000

BAY-5000 (example 32) is a pyrimidinedione derivative.

For research use only. Not for human or veterinary use.

Research area Cancer
Purity >98% Stock Inquire

Description

BAY-5000 (example 32) is a pyrimidinedione derivative. BAY-5000 can be used in the synthesis of cancer-related reagents.

Biological activity

Gilmelisib is an antineoplastic. Gilmelisib is a PI3K inhibitor (IC50 <1 nM for PI3K p110α).

Identifiers

SMILES
CC(C=CC=C1)=C1OC2=C(Cl)C3=C(C=CC=C3)C(N4C(NC(C(F)(F)F)=CC4=O)=O)=C2
InChIKey
UNSHMXUHOHBLIQ-UHFFFAOYSA-N

Specifications

MW (average)
446.8060
Formula
C22H14ClF3N2O3
CAS No.
2639435-48-4
Physical state
Solid
Color
Off-white to light yellow
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃ 3 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

In vitro
DMSO : 250 mg/mL

References

[1]. Bouche Lea Aurelie, et al. Pyrimidinedione derivatives: World Intellectual Property Organization, WO2021063821[P].2021-04-08.

Same research area

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