ALK/BH5-IN-3 free base · Synonyms: ALKBH5 inhibitor 2 (Cpd 20m)
ALKBH5-IN-3 is a selective, cell active ALKBH5 inhibitor.
For research use only. Not for human or veterinary use.
ALK/BH5-IN-3 structure
CAS No.: 1505579-77-0
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 100 mg | USD 416.00 | BP-02399-100mg | In stock | Get quote |
| 250 mg | USD 832.00 | BP-02399-250mg | In stock | Get quote |
| 500 mg | USD 1,330.00 | BP-02399-500mg | In stock | Get quote |
| 1 g | USD 2,130.00 | BP-02399-1g | In stock | Get quote |
| 2 g | USD 3,400.00 | BP-02399-2g | In stock | Get quote |
| 3 g | USD 4,090.00 | BP-02399-3g | In stock | Get quote |
| 5 g | Inquire | BP-02399-5g | In stock | Inquire |
Need another size or custom synthesis? Request a quote.
Description
ALKBH5-IN-3 is a selective, cell active ALKBH5 inhibitor with an IC50 of 0.021 μM. ALKBH5-IN-3 stabilizes ALKBH5 in HepG2 cells, and increases m 6A level in intact cells. ALKBH5-IN-3 can be used as a versatile chemical probe to explore the biological function of ALKBH5. ALKBH5-IN-3 can be used for the research of Cancer .
Biological activity
In Vitro ALKBH5-IN-3 (Compound 20m) (0.3-10 μM; 72 h) increases m6A levels in HepG2 cells. ALKBH5-IN-3 (100 μM; 3 h) stabilizes ALKBH5 in HepG2 cells.
Identifiers
- SMILES
-
O=C(C1=NN(C2=CC=CC(C(F)(F)F)=C2)C(O)=C1)O - InChIKey
-
VBTBURGKMCKOJC-UHFFFAOYSA-N
Specifications
- MW (average)
- 272.1801
- Formula
- C11H7F3N2O3
- CAS No.
- 1505579-77-0
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20°C, 3 years ; In solvent -20°C, 1 month
Solubility
Soluble in DMSO : 31.25 mg/mL