PF-07220060 free base · Synonyms: CDK4/6-IN-6

PF-07220060 is a potent CDK4/CDK6 inhibitor.

For research use only. Not for human or veterinary use.

Target CDK6 CDK4

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

PF-07220060 structure

CAS No.: 2380321-51-5

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
500 mg	USD 585.00	BP-02226-500mg	In stock	Get quote
1 g	USD 885.00	BP-02226-1g	In stock	Get quote

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Description

PF-07220060 (CDK4/6-IN-6) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively. WO2019207463A1 (example A94)

Specifications

MW (average): 463.9330
Formula: C₂₂H₂₇ClFN₅O₃
CAS No.: 2380321-51-5
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

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