M2N12 free base
M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase inhibitor.
For research use only. Not for human or veterinary use.
M2N12 structure
CAS No.: 2376577-06-7
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 50 mg | USD 460.00 | BP-02005-50mg | In stock | Get quote |
| 100 mg | USD 670.00 | BP-02005-100mg | In stock | Get quote |
| 250 mg | USD 1,080.00 | BP-02005-250mg | In stock | Get quote |
| 500 mg | USD 1,580.00 | BP-02005-500mg | In stock | Get quote |
| 1 g | Inquire | BP-02005-1g | In stock | Inquire |
Need another size or custom synthesis? Request a quote.
Description
M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09 μM. M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM, respectively. M2N12 has anti-tumor activity and can be used for cancer research.
Biological activity
M2N12 (0-20 μM; 72 hours) has cytotoxic activity against five tumor cell lines and a normal cell line including A-549, MDA-MB-231, KB, KB-VIN, MCF-7 and HBE (IC50=3.92 μM, 4.63 μM, 5.05 μM, 6.81 μM, 4.71 μM and 6.00 μM, respectively)
Identifiers
- SMILES
-
O=C1C(Cl)=C(C(C2=NC=CC=C12)=O)NCC3=CN(CC4=CC=C(C)C=C4)N=N3 - InChIKey
-
BDBIMDYALUJAPR-UHFFFAOYSA-N
Specifications
- MW (average)
- 393.8260
- Formula
- C20H16ClN5O2
- CAS No.
- 2376577-06-7
- Physical state
- Solid
- Color
- brown to red
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Solubility
Soluble in DMSO : 11.11 mg/mL