Petrelintide acetate salt form · acetate (1:x) · Parent Petrelintide · Synonyms: ZP8396 acetate
Petrelintide (ZP8396) is an amylin analog as an alternative to GLP-1 receptor agonists.
For research use only. Not for human or veterinary use.
Target
Amylin Receptor
Area
Metabolic Disease
Purity >98%
Description
Perelintide (ZP8396) acetate is an amylin analog that shows potential for reducing body weight. Petrelintide can be used in diabetes research. Petrelintide demonstrates agonistic activity against hAMY3R and hCTR in HEK-293 cells, with EC50 of 2.997 and 9.215 nM, respectively.
Specifications
- MW (average)
- 4191.6900 (free base)
- Formula
- C185H305N49O61.xC2H4O2
- CAS No.
- 2766385-23-1 (free base)
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Room temperature in continental US; may vary elsewhere.
- Storage
- Powder -20°C 2 years; 4°C 1 year; In solvent -80°C 6 months; -20°C 1 month
Solubility
Soluble in water
- In vitro
- Soluble in DMSO
Documents
References
[1]. JON G, et al. 1668-P: Novel Once-Weekly Amylin Analog Petrelintide (ZP8396) Is Well Tolerated with Improved GI Tolerability after Multiple Dosing, Diabetes, 2024;73(Supplement_1):1668-P
[2]. BILL V, et al. 1661-P: Petrelintide (ZP8396) Selectively Reduces Intake of High-Fat Diet in DIO Rats. Diabetes 14 June 2024; 73 (Supplement_1): 1661-P.